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The Pill That Prevents HIV Is As Safe As Daily Aspirin

Taking Truvada every day to prevent HIV isn’t any more dangerous than taking a daily aspirin to prevent heart attacks, a new study finds.

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Truvada

People who take Truvada, the once-a-day pill that prevents HIV, are no more at risk for dangerous side effects than those who take an aspirin a day to prevent heart attacks, according to a new study.

Researchers compared Truvada and aspirin by looking at the drugs’ risk profiles in large, published studies. Although the two drugs come with distinct side effects — Truvada most commonly causes dizziness, vomiting, and weight loss, whereas aspirin is most commonly associated with bleeding problems — the frequency of side effects is roughly equivalent.

But the drugs have very different reputations, among both doctors and the general public. Century-old aspirin, when taken as a preventative tool against heart attacks, is viewed as an everyday medication, no big deal. But Truvada, also known as pre-exposure prophylaxis (or PrEP), is a new pill, intertwined with the loaded issues of HIV and sex habits, and mired in uncertainty.

“Everyone’s got aspirin in their medicine cabinet,” Jeffrey Klausner, professor of medicine and public health at the University of California, Los Angeles, and lead author of the study, told BuzzFeed News. “But as a physician I’ve seen people come into the hospital and die from aspirin overdoses — people can be allergic.”

The side effects of each drug are markedly different, Klausner noted, and affect different organs. But after crunching the numbers, he said, “it really looked like I could say Truvada compared favorably, in terms of its safety profile, to aspirin.”

An estimated 52% of American adults aged 45 to 75 are prescribed a daily aspirin to prevent cardiovascular and gastrointestinal diseases, including heart attacks and cancer.

Truvada, which was approved by the FDA in 2012, has been shown to have roughly 92% efficacy in preventing transmission of HIV. The CDC estimates that about 1.2 million Americans are at high enough risk for contracting HIV that they should be prescribed the drug. But only about 21,000 currently get it.

According to Klausner, who trains doctors around the country on how to treat and prevent HIV, much of this has to do with ambivalence about prescribing otherwise healthy individuals a daily pill.

“A lot of the concerns I hear from providers are about safety,” Klausner said. “There have been continued voices saying, ‘Wouldn’t it just be better if people used condoms, or reduced their number of partners?’ Those are important strategies, but they don’t work for everyone.”

The issue of doctor awareness about PrEP is one of the biggest barriers to its wider use.

The new study “is an interesting thought experiment,” Dawn Smith of the CDC’s Division of HIV/AIDS Prevention, told BuzzFeed News. But, she added, “I’m not sure it addresses the safety concerns that some clinicians have.”

Smith noted a CDC study showing that in 2015, about one-third of primary care doctors and nurses had never heard of Truvada. Beyond the lack of awareness, she said, doctors don’t want to cause any side effects, no matter how minor, in otherwise healthy patients.

In his analysis, Klausner looked at the “NNH” — or “number needed to harm” — meaning the number of people who take the drug before one person experiences a harmful side effect. The NNH for Truvada in gay men or transgender women was 114 for nausea and 96 for unintentional weight loss. In women, side effects appeared more frequently, with 1 in 56 women experiencing nausea, 1 in 41 vomiting, and 1 in 36 mildly elevated liver enzymes.

Rarer adverse events for Truvada include kidney problems and a small decrease in bone mineral density, but Klausner notes that both of those effects have been shown to be reversible once the medication is discontinued.

In contrast, aspirin had an NNH of 15 for bleeding problems and 20 for easy bruising. Rarer problems included ulcers and other gastrointestinal problems.

Because it’s so much older, aspirin has been tested in many more people with many more years of follow-up, Klausner noted. Because Truvada is a relatively new drug, it will take awhile to accrue the data needed to make its long-term safety bulletproof.

In the meantime, however, Klausner hopes more doctors will educate themselves about the HIV prevention drug. And after that, he said, “we should work to make it the same price as aspirin.”

Complete Article HERE!

What’s going on w/me?

Name: Paul
Gender: Male
Age: 59
Location: Rhode Island
Dear Dr Dick: I am a 59 yo man, married, masculine and very much attracted to women. I have, however, in the past few years felt an attraction to men as well. I can remember as a pre-puberty boy being turned on to other boys in magazines. Watching male porn does nothing for me and I have no desire to have anal sex. But I do often fantasize about being with a naked man and performing oral sex. I am in my second marriage, which like the first, is not very happy and there is virtually no physical relationship. I have never been much of a “ladies man” although I am very outgoing and have a good sense of humor. Is my inability to score with women turning me towards men, as they are easier to meet? I have not acted on any fantasy although I do go to a gay massage therapist and very much enjoy his hands on my body and the great hand job at the end. Too much to lose to pursue men. What’s going on w/me?

A common enough complaint, Paul. You’re apparently awakening to the realization that there is more to your sexuality than you’ve allowed yourself to consider in the past. And no, I don’t think you’re interest in men is connected to your track record with women. But it certainly could be the other way around. You aren’t overly successful with the ladies, because you’re much more interested in the gents. Does that sound more like it?

You say you haven’t acted on your newly uncovered fantasies, but you do, from time to time, get a nice hand job from the gay masseur you frequent. Aren’t you just splitting hairs with this artificial and arbitrary boundary? And aren’t you saying that if you’re not the “active” partner, you have some credible deniability? Bollocks!  I gotta tell ya, that kind of thinking make my flesh crawl.try-it-youll-like-it

It appears to me that you’re not gonna be satisfied till you finally get some mighty fine cock in your mouth. And there’s any number of ways you can get that to happen. You’re already seeing a sex worker for your massages; why not look for one who will let you blow him. Look for an escort or ask your masseur for a referral. Hell, he may even oblige you himself. All ya gotta do is be upfront with what you are looking for. Tell the provider you are unversed in the whole cock sucking department, but you’ve been wanting to try it. Remember, you’ve not committing yourself to anything, you’re just doing some research. Right?

My only concern is that you seem to have already put the kibosh any possible research when you say: “Too much to lose to pursue men.” Oh really? How much is too much? Is your over all happiness, your sexual fulfillment, or your integrity TOO MUCH? Think about it some and get back to me.

Good luck

Weed Lube Is Not Lube

But It Apparently Works Magic on Vaginas

Sensual cannabis

Sensual cannabis oil magnifies sensitivity and sensation.

People are freaking out over weed lube. Rightly so, I guess, because it’s apparently magical. But while weed lube is lubricating, it isn’t lube, per se. As in, its main use is not to facilitate intercourse.

Lena Davidson, the marketing manager for botanicaSEATTLE—the company behind BOND Sensual Oil—told me that what most people would call weed lube is really more of a massage oil. Like other cannabis topicals and unlike a traditional lube, it takes 20 to 40 minutes to work and is a self-contained experience that can be enhanced by sex. Being oil-based, it is also not latex safe. People call it weed lube, she says, because we’re basically all teenage boys and we can’t talk about weed or sex without snickering.

As much fun as it is to giggle about getting one’s “pussy stoned” (as Vice did), weed lube is serious business. Sensual cannabis oil, as it is more accurately called, has all sorts of awesome ramifications for sexual equity. Davidson pointed out that while there are more than 26 products approved by the FDA to treat sexual dysfunction in men, there is only one approved for women, and it is the subject of much controversy. Sensual cannabis oil is a long way off from FDA approval, but judging from testimonials thus far, it seems to be doing consistently what that one drug does inconsistently: increasing female sexual pleasure. Women who have used BOND reported “ethereal, long-lasting, and out of this world” sexual experiences, and the ability to rapidly “peak… and then do it again quite quickly,” according to testimonials on BOND’s website. Multiple orgasms are apparently common.

Cannabis-LubeHow does it work? Davidson writes: “THC is absorbed through the mucous membranes that are in high concentrations in a woman’s vagina. Once applied and absorbed, THC acts locally on the cannabinoid receptors, much like an edible. Functionally, the THC dilates the capillaries and increases blood flow in the smallest blood vessels in our body—this enhanced microcirculation magnifies sensitivity and sensation.” (She also mentioned that this same capillary reaction is what causes stoney red eyes.) The experience is not like the head high one gets from smoking or eating weed, but rather a localized sensation of pleasure, users report.

It’s also important to note that, at least here in Washington, sensual cannabis oil is safe. Davidson cautioned that not all weed lube is created equal, but BOND and Ethos Extracts‘ Temptress are made in a WSDA-approved kitchen with food-grade organic coconut oil and ultra-pure cannabis extracts. Coconut oil, though unfriendly to latex, is ideal for internal use because of its natural pH-balancing and antimicrobial qualities.

While the potential to help women with issues such as vaginismus (vaginal pain) and low libido is great in its own right, perhaps the most exciting thing about sensual cannabis oil is that it is a decidedly non-heteronormative phenomenon. What I mean by that is it takes the focus off of the penis as the center of sexual pleasure, where it has been for far too long.

My good friend Kat, a big proponent of sensual cannabis oil and the source of much of my education on feminism, put it thusly: “It’s unfortunately common during heteronormative sex that women feel like their partner’s ejaculative experience is the focal point. I’m usually acutely aware of the other person’s level of satisfaction, which takes me away from my own body. With the weed lube, I’m like, ‘Fuck yeah, I’m getting it and it feels fucking amazing.’ I’m actually relaxed and stimulated enough to invest in my own delectation.”Cannabis

And though much has been made of sensual cannabis oil not working for men, that’s not entirely true. It doesn’t work well for selfish straight men who are only interested in receiving blowjobs and having vaginal intercourse (because the penis does not absorb the cannabis oil in the same way that the vagina does). It does, however, work really well for men (and women) who are into anal play, as the absorption of THC through the back door is rapid. Used anally, sensual cannabis oil does not offer the same direct enhancement of physical sensation as it does to the vagina, but it does get you high as fuck, which enhances sex in its own right. Also, anyone willing to perform a little enthusiastic cunnilingus—as any self-respecting straight dude should be—will get a light edible-style buzz. Basically, anything that has not traditionally been part of the penis-obsessed, heteronormative sexual canon is made better with sensual cannabis oil. If that isn’t sweet sexual justice, I don’t know what is.

Speaking of sexual justice, sensual cannabis oil also works well for older women—another segment of the population whose sexual lives are often not valued in the heteronormative conversation. Women’s bodies produce less lubrication during and after menopause, and older women can also suffer from decreased libido and other sexual difficulties—problems that sensual cannabis oil can help with. Edward Lafferty, Ethos’s CEO, said that women older than 45 and gay men make up the bulk of his business for the Temptress oil. During product testing of BOND, “nearly every woman had a ‘Eureka!’ moment,” said Davidson. And “for women who had felt estranged from their innate sexuality by age or physical conditions, it instigated a wave of natural physiological desire.”

Davidson worries that those who might benefit most from sensual cannabis oil will not do so because of the continued cultural awkwardness around weed, sex, and weedy sex. She pointed out that women are statistically less likely to try cannabis products in general, let alone walk into a weed store and ask a scruffy dude about something as personal as their sexual health. What’s more, sensual cannabis oil is still perceived as a sex-shop novelty—something for young party people to rub on one another after the rave, not something that can help women have more sexually fulfilling lives.

But, as Lafferty put it, “The people who use it need it. It’s important. We can be squeamish, but it works.” So let’s get one thing straight: Weed lube isn’t lube, and it’s also not a novelty. According to many of those who’ve tried it, it’s a godsend. recommended

Complete Article HERE!

Notching the belt

Hey Doc,

So I’ve asked you a question anonymously before and you were a huge help so here I am again.
My names Mike and I’m 17 years old. For some reason it takes me a ridiculously long time to “finish” with my girlfriend. It’s not her, because this has happened with about 4 or 5 other women before her. It’s an annoying flaw that it takes me about 90 minutes to finish, if I finish at all. My GF and I get tired and eventually just stop because it’s too tiring and just plain tiresome. Is it performance anxiety or something? My first time having sex was anal with a girl, and I have done anal with girls many times before so it was a lot tighter than vaginal intercourse, not sure if that affects anything… I am really tired of lasting so long; I just want to be done when she is, much earlier.

I’ll be glad to answer any questions or anything you might need to know,
Thank you so much in advance, Mike.

finger fuck00445Where to begin, Mike? You’re 17, you’re having performance problems with your GF and you have had with about 4 or 5 other women before her. Holy Cow! you certainly are a sexually precocious lad, aren’t you?

I can’t help but notice a bit of sexual bravado in your message. I don’t know if that’s intended or if it’s more of a subliminal message. Either way, I have a feeling that there is some belt notching goin on here and that may be the root of your problems.

Here’s why I say this. There is nothing in your message that communicates that the sex you’re having is fun, or that it’s play. All I hear is that you’re a young man on a mission. You want to get off in a timely fashion and you’re currently being frustrated in that pursuit. You sound so goal oriented and your sex sounds like a task, rather than a playful adventure.

Us men folk get like this sometimes; and we’re the poorer for it. We’re all about solving a problem instead of enjoying the moment. The curious thing about this is that enjoying the moment is often the best way to solve a sexual performance problem.bryan_tony_box

When I hear men and/or women talking about their sex life like it’s work, I know there will be problems ahead. And you, Mike, sound like your sex is way more work than fun. If you were a sex worker or a porn star, I’d understand your predicament. But I suspect that you are neither a sex worker nor a porn star. You are, however, a young man who has, for one reason or another, scuttled all the joy and wonderment from your sex play. And that, my friend, is a crying shame…and at your tender age too. How do you suppose you’ll behave when you’re an old man of 25?

This path you’re on will continue to lead you into a sexual wilderness. You will become increasingly frustrated in your efforts to cum “on time”…and I use that term in quotes, because you’re all about bangin’ something rather than pleasuring and being pleasured by someone.

The comment you make about the difference between butt sex and pussy sex also tells me a lot about the kind of tightness you need to get off. I’d be willing to guess that you have a death grip on your johnson when you wank; am I right? Obviously your average asshole is a tighter orifice than your average pussy. But, if you were really turned on and enjoying the mutual pleasure available to you and your partner, instead of worrying about busting your nut during the fuck itself, you could jettison all those “shoulds” you have when you’re supposed to be enjoying yourself in the company of your lover.

beltWhy not stop what you are doing and take a look at why and how you are doing it. You may surprise yourself with what you find. And if you are man enough, have a heart-to-heart chat with your GF and get her feedback on what she encounters when she fucks you. Again, I’d be willing to guess she’d have some timely advice to offer you on how to fuck and get fucked.

Good Luck

20 Interesting Facts You Never Knew

Everyone took a sexual education course in middle or high school to learn about the “birds and the bees.” However, there are a lot of facts that sex ed teachers leave out. These facts are sometimes the most interesting and the most useful in real-life situations. Here are 20 little known facts about “doing it.”

Patterns In Sexual Desire

Most women have an increase in sexual desire around the time that they ovulate each month. This is nature’s way of making sure the Earth stays well-populated.

It Sounds Gross But…

Semen can be great for the facial pores and can even help with acne. The male-produced “facial cream” can also prevent wrinkles.

Headache

A Headache Is A Bad Excuse

We’ve all heard the cliche “my head hurts” excuse for turning down sex. However, sex often helps with pain, especially with headaches.

We’re Not Judging

Many straight men enjoy having their anal areas stimulated, and that is totally okay! Sexual experts say that the anal areas are packed full of nerves and can make a male orgasm so much better.

1, 2, 3…And They Keep Coming!

Women can orgasm an unlimited amount of times. Men generally need a period of time after orgasming to recover. However, women need barely any time and are ready to go as many times as they please.

Men Are Erect…A Lot

It is said that many men experience about 11 erections every single day. While they may not be raging every single time, it does happen pretty often.

Celery Can Arouse

Yes, celery. The pheromones in celery can cause arousal in men. In addition to the arousal, the vegetable also makes men who eat it more attractive to women.

The Left Side Is The Best Side

A group of scientists found the upper left quadrant of the clitoral head is the most pleasurable spot to touch. So, it’s okay to tell him to go “a little to the left.” It’ll be sure to make the sex even more enjoyable.

Orgasms Are Different

A man’s orgasm lasts about 22 seconds while a woman’s lasts about 18. It is also very common for it to be uncomfortable to pee after having sex because of an antidiuretic hormone that prevents urine from freely flowing.

Sex Can IMPROVE With Age

Sexual attraction is a life-long drive. The reason most older people don’t have sex very often is that there is a lack of opportunity to have sexual encounters.

Get Your Heart Going

Sex is a great way of getting in your daily cardio exercise. During an orgasm, heart rates can reach between 140 and 180 bpm.

spunklube

Lube Can Make A Difference

While lube is considered a sex tool for older people, many sexual experts say that a little lubricate can make the difference between pain and pleasure during sex. This doesn’t mean the woman is not turned on. Natural “lube” can come and go without any warning.

Penetration Is NOT The Secret

Most women do not orgasm from penetration alone. The majority of women need some type of clitoral stimulation to reach their climax. It has nothing to do with size or penetration.

Everything Expands

The penis is not the only thing that grows during a sexual encounter. In fact, the testes grow by 50% and the vagina can double in size when aroused.

More Sex Makes You More Appealing

After having sex, a woman’s estrogen levels double. When estrogen levels are higher, a woman’s hair can look shinier and her skin can even feel softer.

Not Only People Can Be Arousing

Some people have sexual attraction to objects instead of specific people. There is a woman known to be sexually aroused by the Eiffel Tower.

Have Sex, Live Longer

Scientists have found that orgasms can actually prolong your life. That’s right, the more sex you have, the longer you can live.

Humans & Dolphins Alike

As far as sex is considered, dolphins and humans have one key fact in common. The two mammals are the only animals in the world that have sex for pleasure.

Sex Everyday Keeps The Doctor Away

Sex can actually help you stay healthy. Many doctors believe this is because sex can lower blood pressure and greatly decrease stress levels.

It’s Like Two Puzzle Pieces

Not every penis, or vagina, is the same. If a guy is too large, women can control penetration by changing positions. If he is too small, there are many toys, etc that couples can invest in.